Events
Past Event
WED@NICO SEMINAR: Chris Kuzawa, Northwestern University "Fetal developmental plasticity as signal-noise problem: the case of nutrients and stress physiology"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
//
Lower Level, Chambers Hall
Details
Speaker:
Chris Kuzawa, John D. MacArthur Professor, Department of Anthroplogy, Northwestern University
Title:
Fetal developmental plasticity as signal-noise problem: the case of nutrients and stress physiology
Abstract:
The stage of human development marked by greatest sensitivity and developmental plasticity occurs prior to birth, when the developing embryo and fetus are embedded within the highly regulated intrauterine environment maintained by the mother’s body. In this talk, I will discuss the timescales of maternal experience that modify this milieu, with a focus on two crucial systems: nutrient metabolism and stress physiology. I will argue that elaborate and redundant maternal buffering of nutrient delivery uncouples short term variability in what the mother eats – whether negative changes like famine or improvements in the form of nutritional supplementation - from fetal nutrition and development, which instead track changes in maternal nutrition on a longer, generational timescale. In contrast, stress physiology is by design highly responsive to the mother’s short-term experiences and the responsiveness of these systems have broad spill-over effects on fetal development, thus linking offspring biological and health outcomes to acute variability in maternal stress during pregnancy. I will discuss the relevance of these principles for understanding the evolution of the flow of ecological information across generations and the design of interventions aimed at harnessing early life plasticity to improve future population health.
Speaker Bio:
Chris Kuzawa and his students and collaborators use principles from anthropology and evolutionary biology to gain insights into the biological and health impacts of human developmental plasticity. Thier primary field research is conducted in Cebu, the Philippines, where they work with a large birth cohort study that enrolled more than 3,000 pregnant women in 1983 and has since followed their offspring into adulthood (now 30 years old). They use the nearly 3 decades of data available for each study participant, and recruitment of generation 3 (the grandoffspring of the original mothers), to gain a better understanding of the long-term and intergenerational impacts of early life environments on adult biology, life history, reproduction, and health. A theme of much of this work is the application of principles of developmental plasticity and evolutionary biology to issues of health. Professor Kuzawa is a member of the National Academy of Sciences and American Academy of Arts and Sciences.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/91503621521
Passcode: NICO23
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems and data science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, February 22, 2023 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Lightning Talks w/ Northwestern Scholars!
Northwestern Institute on Complex Systems (NICO)
12:00 PM
//
Lower Level, Chambers Hall
Details
Speakers:
Yessica Herrera, Visiting Scholar, Northwestern Institute on Complex Systems
Talk Title: The Body Speaks: Visual Patterns of Psychological Stress
Aakriti Kumar, Post-Doctoral Fellow, Northwestern Institute on Complex Systems
Talk Title: Evaluating Elements of Empathic Communication with Experts, Crowds, and Large Language Models
Tingyu "Mark" Zhao, PhD Student, Industrial Engineering and Management Sciences
Talk Title: Noise Filtering in Complex Networks
Sign Up:
Sign up to present at a future Lightning Talk session. NICO Lightning Talks are open to graduate students, postdoctoral fellows, and visiting scholars.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/95387714084
Passcode: NICO25
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 14, 2025 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Rosemary Braun, Northwestern University "The Scale of Life"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
//
Lower Level, Chambers Hall
Details
Speaker:
Rosemary Braun, Associate Professor, Department of Molecular Biosciences, Northwestern University
Title:
The Scale of Life
Abstract:
Living systems exhibit surprising and beautiful self-organization at all scales. At the atomic level, proteins self-assemble into macromolecular complexes. The function of these machines is orchestrated within the cell by regulatory networks, whose activity is in turn dictated by, and coordinated with, the cells environment. This coordination takes place across large spans of space and time: the size and lifetime of organisms as large as the blue whale. Populations and ecosystems of many organisms in turn exhibit remarkable emergent dynamics. Today, advances in single-cell assays enable us to probe the molecular state of every cell in a sample in high-dimensional detail. But is this the correct scale at which to probe living systems? What can we learn from this data, and how can we abstract from the microscopic details to macroscopic phenotypes? In this talk, I will discuss some of our recent work bridging the cell and tissue/organism scales, and discuss some challenges and opportunities for the future.
Speaker Bio:
Rosemary Braun is an Associate Professor of Molecular Biosciences, Applied Mathematics [ESAM], and Physics at Northwestern University. A theoretical physicist by training, she earned her PhD in Physics from the University of Illinois, followed by a Masters in Biostatistics from Johns Hopkins University. She completed her postdoctoral training at the National Cancer Institute (NIH) before joining Northwestern as a faculty member. Today, she works at the intersection of statistics, mathematics, and biology to develop computational tools for analyzing high-dimensional data. In addition to her Northwestern affiliations, she is also Associate Director of the National Institute for Theory and Mathematics in Biology, as well as external faculty of the Santa Fe Institute.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/97015976754
Passcode: NICO25
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 21, 2025 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)