Events
Past Event
WED@NICO SEMINAR: Luis M Rocha, Binghamton University "Redundancy in the Structure and Dynamics of Complex Systems"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speaker:
Luis M Rocha, George J. Klir Professor of Systems Science, Binghamton University - State University of New York
Title:
Redundancy in the Structure and Dynamics of Complex Systems
Abstract:
As the current COVID-19 pandemic demonstrates, our social lives and overall public health depend heavily on interactions that cross scales from the molecular networks of minute pathogens to all our transportation, health, economy, ecology, and governance networks. The study of networks that quickly link the tiniest virus to the most potent economy has been pursued by the interdisciplinary field of complex networks & systems (CNS), which aims to find and simplify commonalities among networks that are measured and studied at various scales in the natural and social sciences. While most advances in CNS have come from the study of patterns of connectivity (network structure), which provides many insights into the organization of complex systems, a critical gap remains in understanding how the structure of networks affects the dynamics of complex systems. For instance, in brain networks we do not know how synaptic connectivity leads to the dynamical patterns of functional connectivity that are responsible for human behavior. Likewise, while we know much about the connectivity of gene and protein regulation from existing systems biology models, the structure of interactions from these models is not sufficient to predict regulatory dynamics or derive control strategies that allow us, for instance, to revert a diseased cell to a healthy state.
Our lab has been working to addresses this critical gap with an original insight: in addition to patterns of connectivity and patterns of dynamics, there are important patterns of redundancy which dictate how structure affects dynamics in networks. Regarding structural redundancy, we present the distance backbone of a network: a sub-graph that is sufficient to compute all shortest paths on a weighted graph. The size of the backbone subgraph, in relation to the size of the original graph, defines the amount of redundancy in the network: edges not on this backbone are superfluous in the computation of shortest paths. We demonstrate that the distance backbone is very small in large networks across domains including social contact (in epidemiological models), gene regulation (in evolution, development and disease) and the human brain connectome, revealing that network robustness to attacks and failures seems to stem from surprisingly vast amounts of redundancy. Regarding dynamical redundancy, we present the effective graph, a probabilistic graph that captures the nonlinear interactions that are sufficient for biochemical network regulation, signaling, and control. Using 78 experimentally validated models derived from systems biology, we demonstrate that redundant pathways are prevalent in biological models of biochemical regulation and show that the effective graph provides an accurate explanation of how dynamical perturbation and control signals, such as those induced by cancer drug therapies, propagate in biochemical pathways.
Speaker Bio:
Luis M. Rocha is the George J. Klir Professor of Systems Science at the Thomas J. Watson College of Engineering and Applied Science, Binghamton University (State University of New York), where he leads the Complex Adaptive Systems and Computational Intelligence (CASCI) lab. He is also director of the Center for Social and Biomedical Complexity, between Binghamton University and Indiana University, Bloomington. His research is on complex networks & systems, computational & systems biology, and computational intelligence.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/92190854861
Passcode: NICO2022
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems and data science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 11, 2022 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Lightning Talks with NU Scholars!
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
May 20th Speakers:
Yulin Yu, Postdoctoral Fellow, Kellogg School of Management
Feihong Xu, PhD Candidate, McCormick School of Engineering
Maalvika Bhat, PhD Student, School of Communication
Rochana Chaturvedi, Postdoctoral Fellow, Kellogg School of Management
NICO Lightning talks are open to Northwestern graduate students, postdoctoral fellows, and visiting scholars! If you are interested in signing up for a future session, please fill out this short survey.
Talk Titles and Abstracts:
Yulin Yu
Postdoctoral Fellow
Kellogg School of Management &
Northwestern Institute on Complex Systems
Human–AI Creative Pathways: How People and Machines Differ in Creative Strategy
Generative AI offers the promise of amplifying creativity by recombining knowledge at a scale far beyond human capacity, yet humans still hold key advantages in flexibility and contextual reasoning. To understand how each achieves novelty, we analyzed more than 5,000 responses to the Divergent Association Task from both humans and AI systems using network-based methods. We find that while individual humans use fewer and simpler conceptual categories than machines, the collective diversity of human ideas is substantially higher. Human creative pathways tend to follow a one-directional but highly unpredictable trajectory, whereas AI systems rely on repetitive, back-and-forth exploration patterns. Finally, both humans and machines show anchoring effects—early ideas shape later responses—but in opposite ways: humans anchor low, while machines anchor high.
Feihong Xu
PhD Candidate
Engineering Sciences & Applied Mathematics
McCormick School of Engineering
A Well-Calibrated Model Similarity Measure for Arbitrary Neural Networks
Deep learning approaches have transformed biological and biomedical image analysis, but model opacity and fragility remain major obstacles to trustworthy use. One barrier is the lack of a well-calibrated measure of similarity across arbitrary neural networks trained with different architectures, checkpoints, random initializations, and training strategies. Existing notions of model similarity span functional and representational domains, often rely on heuristic assumptions, and are susceptible to spurious signals introduced by probing samples, making principled cross-model meta-analysis difficult. Here, we clarify prevailing notions of deep neural network similarity and benchmark their robustness under extensive out-of-distribution perturbations. We then introduce the Ahmad RV coefficient on chain weight matrices (wARV), a theoretically grounded weight-space similarity measure that combines chain-normalized weights with the RV coefficient. wARV is sample-agnostic, symmetric, computationally efficient, and better calibrated than current measures. Across benchmarks varying random initialization, training checkpoint, architecture, and training strategy, wARV more faithfully tracks functional similarity while avoiding confounding effects from probing data. Applying wARV to deep neural network models on both generic and medical image classification tasks, we uncover substantial learning heterogeneity and instability even among models with similar predictive performance.
Maalvika Bhat
PhD Student
Technology and Social Behavior
School of Communication &
McCormick School of Engineering
Scholars See Clickbait as a Greater Threat to Science Than to Their Own Work
As scientific research competes for attention in a media landscape driven by sensationalism, the risks of misrepresentation grow. This study examines whether academics, while widely recognizing clickbait as a threat to science broadly, tend to downplay its relevance to their own work. Surveying 5,603 U.S.-based researchers, we find a consistent perception gap between systemic and personal risk, one that varies by career stage and disciplinary context. Early-career scholars show a pronounced version of this asymmetry: they express heightened concern about clickbait’s harms to science while rating its relevance to their own work as comparatively lower, a pattern that leaves them most exposed at a stage when reputational stakes are highest.
Rochana Chaturvedi
Postdoctoral Fellow
Kellogg School of Management &
Northwestern Institute on Complex Systems
Who Gets the Callback? Generative Artificial Intelligence and Gender Bias
Large language models are increasingly embedded in hiring workflows, raising concerns about their potential to amplify societal biases — yet how these biases manifest within and across occupations, and the role of model 'personality' in shaping these biases, remains unexplored. We introduce a three-part attribution framework applied to 332,044 real-world job ads, measuring gender-based callback bias, associations of skills and traits with gendered stereotypes in LLMs, and the effect of simulated recruiter personas. We find that LLMs systematically favor men, especially in higher-wage roles, with their decisions tracking traditional gendered language cues in job postings. Notably, assigning a low-agreeableness persona reduces model bias, implicating sycophancy as a mechanism reinforcing societal stereotypes; at the same time, controversial personas trigger internal guardrails leading to more cautious and less-biased outputs. These findings highlight how alignment choices in AI-driven hiring systems shape bias, with important implications for fairness and diversity.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/98031689779
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, networks, and artificial intelligence. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 20, 2026 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)