Events
Past Event
WED@NICO WEBINAR: Mercedes Pascual, University of Chicago "From eco-evolutionary assembly to network structure in a hyper-diverse host-pathogen system"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
Details
Speaker:
Mercedes Pascual, Professor, Department of Ecology and Evolution, University of Chicago
Title:
From eco-evolutionary assembly to network structure in a hyper-diverse host-pathogen system
Abstract:
How important are specific ecological interactions to the assembly of a diverse community of species? Can coexistence reflect instead neutral assembly, simply resulting from stochastic birth-death processes? What signatures of diversity patterns can help us distinguish among these two explanations? These long-standing questions from Ecology and its interplay with Evolution, can be similarly asked at a different level of organization for strain diversity within a pathogen population. I do so here for the malaria parasite P. falciparum in high-transmission regions. Strains compete for hosts in a frequency-dependent manner as hosts acquire specific immune memory against their variable surface antigens. Such competitive interactions result in negative frequency-dependent selection. I show that networks describing patterns of limiting similarity can help us identify the importance of this non-neutral process to coexistence. Implications for pathogen persistence and responses to perturbations are discussed, as well as similar questions in another eco-evolutionary system.
Speaker Bio:
Mercedes Pascual is a Professor in the Department of Ecology and Evolution at the University of Chicago, and an external faculty of the Santa Fe Institute. Dr. Pascual is a theoretical ecologist interested in the population dynamics of infectious diseases, their response to changing environments and their interplay with pathogen diversity. She is also interested in the structure and dynamics of large interaction networks in ecology and epidemiology. Dr. Pascual received her Ph.D. degree from the joint program of the Woods Hole Oceanographic Institution and the Massachusetts Institute of Technology. She was awarded a U.S. Department of Energy Alexander Hollaender Distinguished Postdoctoral Fellowship for studies at Princeton University, and a Centennial Fellowship in the area of Global and Complex Systems by the James S. McDonnell Foundation for her research at the University of Michigan. She received the Robert H. MacArthur award from the Ecological Society of America. She is a fellow of the American Association for the Advancement of Science and a member of the American Academy of Arts and Sciences.
Webinar:
https://northwestern.zoom.us/j/95743710812
Passcode: NICO2022
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems and data science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, February 16, 2022 at 12:00 PM - 1:00 PM
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Lightning Talks w/ Northwestern Scholars!
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speakers:
Yessica Herrera, Visiting Scholar, Northwestern Institute on Complex Systems
Talk Title: The Body Speaks: Visual Patterns of Psychological Stress
Aakriti Kumar, Post-Doctoral Fellow, Northwestern Institute on Complex Systems
Talk Title: Evaluating Elements of Empathic Communication with Experts, Crowds, and Large Language Models
Tingyu "Mark" Zhao, PhD Student, Industrial Engineering and Management Sciences
Talk Title: Noise Filtering in Complex Networks
Sign Up:
Sign up to present at a future Lightning Talk session. NICO Lightning Talks are open to graduate students, postdoctoral fellows, and visiting scholars.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/95387714084
Passcode: NICO25
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 14, 2025 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Rosemary Braun, Northwestern University "The Scale of Life"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speaker:
Rosemary Braun, Associate Professor, Department of Molecular Biosciences, Northwestern University
Title:
The Scale of Life
Abstract:
Living systems exhibit surprising and beautiful self-organization at all scales. At the atomic level, proteins self-assemble into macromolecular complexes. The function of these machines is orchestrated within the cell by regulatory networks, whose activity is in turn dictated by, and coordinated with, the cells environment. This coordination takes place across large spans of space and time: the size and lifetime of organisms as large as the blue whale. Populations and ecosystems of many organisms in turn exhibit remarkable emergent dynamics. Today, advances in single-cell assays enable us to probe the molecular state of every cell in a sample in high-dimensional detail. But is this the correct scale at which to probe living systems? What can we learn from this data, and how can we abstract from the microscopic details to macroscopic phenotypes? In this talk, I will discuss some of our recent work bridging the cell and tissue/organism scales, and discuss some challenges and opportunities for the future.
Speaker Bio:
Rosemary Braun is an Associate Professor of Molecular Biosciences, Applied Mathematics [ESAM], and Physics at Northwestern University. A theoretical physicist by training, she earned her PhD in Physics from the University of Illinois, followed by a Masters in Biostatistics from Johns Hopkins University. She completed her postdoctoral training at the National Cancer Institute (NIH) before joining Northwestern as a faculty member. Today, she works at the intersection of statistics, mathematics, and biology to develop computational tools for analyzing high-dimensional data. In addition to her Northwestern affiliations, she is also Associate Director of the National Institute for Theory and Mathematics in Biology, as well as external faculty of the Santa Fe Institute.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/97015976754
Passcode: NICO25
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 21, 2025 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)