Events
Past Event
WED@NICO SEMINAR: Alexandra Jilkine, University of Notre Dame " Models of Diffusion-Coupled Oscillators in Cell Biology"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speaker:
Alexandra Jilkine, Assistant Professor, Department of Applied & Computational Math & Statistics, University of Notre Dame
Title:
Models of Diffusion-Coupled Oscillators in Cell Biology
Abstract:
One of the major tasks that a cell faces during its lifecycle is how to spatially localize its components. Correct spatial organization of various proteins (cellular polarity) is fundamental not only for the correct cell shape, but also to carry out essential cellular functions, such as the spatial coordination of cell division. We present a mathematical model of the core mechanism responsible for the regulation of polarized growth dynamics in the model organism, fission yeast. The model is based on the competition of growth zones of polarity protein Cdc42 localized at the cell tips for a common substrate (inactive Cdc42) that diffuses in the cytosol. We consider several potential ways of implementing negative feedback between Cd42 and its GEF in this model that would be consistent with the observed oscillations of Cdc42 in fission yeast. We analyze the bifurcations in this model as the cell length increases, and total amount of Cdc42 and GEF increase. We find that a stable oscillation and a stable steady state can coexist, which is consistent with the experimental finding that only 50% of bipolar cells oscillate. Our model suggests that negative feedback is more likely to be acting through inhibition of GEF association rather than upregulation of GEF dissociation. We consider the differences between the deterministic and stochastic versions of the model, and discuss general conditions for how diffusion can trigger collective synchronous oscillations.
Speaker Bio:
Alexandra Jilkine is an Assistant Professor in the Department of Applied and Copmutational Mathematics and Statistics at the University of Notre Dame. She obtained her Ph.D. in Applied Mathematics from University of British Columbia in 2010. Prof. Jilkine is a mathematical biologist, and her research interests include: mathematical modelling of cell lineages and optimal division patterns for delaying cancer, modeling feedbacks governing stem cell renewal and differentiation, and spatiotemporal behaviour of biochemical circuits.
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems and data science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between.
Live Stream:
Time
Wednesday, May 16, 2018 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Alex Imas, University of Chicago "Agentic Interactions"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speaker:
Alex Imas, Roger L. and Rachel M. Goetz Professor of Behavioral Science, Economics, and Applied AI, University of Chicago, Booth School of Business
Title:
Agentic Interactions
Abstract:
Do human differences persist and scale when decisions are delegated to AI agents? In this talk we will explore an experimental marketplace in which individuals author instructions for buyer-and seller-side agents that negotiate on their behalf. We compare these AI agentic interactions to standard human-to-human negotiations in the same setting. First, contrary to predictions of more homogenous outcomes, agentic interactions lead to, if anything, greater dispersion in outcomes compared to human-mediated interactions. Second, crossing agents across counterparties reveals systematic dispersion in outcomes that tracks the identity and characteristics of the human creators; who designs the agent matters as much as, and often more than, shared information or code. Canonical behavioral frictions reappear in agentic form: personality traits shape agent behavior and selection on principal characteristics yields sorting. Despite AI agents not having access to the human principal's characteristics, demographics such as gender and personality variables have substantial explanatory power for outcomes, in ways that are sometimes reversed from human-to-human interactions. Moreover, we uncover significant variation in "machine fluency"-the ability to instruct an AI agent to effectively align with one's objective function-that is predicted by principals' individual types, suggesting a new source of heterogeneity and inequality in economic outcomes. These results indicate that the agentic economy inherits, transforms, and may even amplify, human heterogeneity. Finally, we highlight a new type of information asymmetry in principal-agent relationships and the potential for specification hazard, and discuss broader implications for welfare, inequality, and market power in economies increasingly transacted through machines shaped by human intent.
Speaker Bio:
Alex Imas studies behavioral economics with a focus on how people understand and mentally represent the choices they are facing. His research explores topics related to how people learn and make choices in settings with risk and uncertainty. He also studies the economics of artificial intelligence and discrimination. Alex’s work utilizes a variety of methods, including controlled laboratory experiments, field experiments, analysis of observational data and theoretical modeling.
Alex is the recipient of the 2023 Alfred P. Sloan Research Fellowship, the Review of Financial Studies Rising Scholar Award, the New Investigator Award from the Behavioral Science and Policy Association, the Hillel Einhorn New Investigator Award from the Society of Judgment and Decision Making, the Distinguished CESifo Affiliate Award, and the NSF Graduate Research Fellowship. He is the co-author, with Richard Thaler, of The Winner’s Curse: Behavioral Economics Anomalies, Then and Now. He is an Associate Editor at the Journal of the European Economic Association and on the editorial board of Psychological Science.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/91389366431
PW: NICO26
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, February 18, 2026 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Todd Florin and Nelson Sanchez-Pinto, Lurie Children's Hospital of Chicago "Pediatric Acute & Critical Care Research & Innovation"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speakers:
Todd Florin, MD, MSCE, Associate Division Head for Academic Affairs & Research, Division of Emergency Medicine, Ann & Robert H. Lurie Children’s Hospital of Chicago; Professor of Pediatrics (Emergency Medicine), Northwestern University Feinberg School of Medicine
L. Nelson Sanchez-Pinto, MD, MBI, Attending Physician, Critical Care, Ann & Robert Lurie Children’s Hospital of Chicago; Associate Professor of Pediatrics (Critical Care) and Preventive Medicine (Health and Biomedical Informatics), Northwestern University Feinberg School of Medicine
Title:
Pediatric Acute & Critical Care Research & Innovation
Abstract:
TBA
Speaker Bios:
Dr. Todd Florin is a founding co-director of the Center for Pediatric Acute and Critical Care Research and Innovation (PACCRI). He is a pediatric emergency medicine physician-scientist with interests in pediatric respiratory infections and expertise in clinical and molecular epidemiology, predictive analytics, and large-scale, multicenter clinical trials in the acute care setting. He is committed to generating and implementing the best evidence to allow for precision care tailored to each patient.
Dr. Nelson Sanchez-Pinto is a founding co-director of the Center for Pediatric Acute and Critical Care Research and Innovation (PACCRI). He is a pediatric critical care medicine physician-scientist with interests in sepsis and expertise in data science and clinical informatics. His goal is to develop, test, and operationalize AI-enabled predictive and prognostic enrichment strategies that can help clinicians provide more personalized and targeted care to critically ill children.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/92586384543
PW: NICO26
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, February 25, 2026 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Ágnes Horvát, Northwestern School of Communication
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speaker:
Ágnes Horvát, Associate Professor, Department of Communication Studies, Northwestern School of Communication
Title:
TBA
Abstract:
TBA
Speaker Bio:
Ágnes Horvát is an Associate Professor in the Department of Communication Studies, (by courtesy) the Computer Science Department of the McCormick School of Engineering, and (also by courtesy) the Department of Management and Organizations of the Kellogg School of Management.
Her research seeks to measure, understand, and forecast the collective behaviour of networked crowds in large-scale socio-technical systems. On the one hand, her current projects investigate the impact of network embeddedness and diversity on scholarly communication. On the other hand, she works on identifying expressions of collective intelligence and opportunities for innovation in crowdsourcing communities. Her research group also develops empirical and theoretical methods to support creativity and predict success in culture industries. This work lies at the intersection of computational social science and social computing. It uses an interdisciplinary data-driven approach that builds on techniques from network science, machine learning, and statistics.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/96701776160
PW: NICO26
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, March 4, 2026 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Steven Franconeri, Northwestern University "Point Taken: A gamified Intervention that Creates Enlightened Disagreements"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
//
Lower Level, Chambers Hall
Details
Speaker:
Steven Franconeri, Professor of Psychology, Weinberg College of Arts & Sciences; Professor of Management and Organizations, Kellogg School of Management, Northwestern University
Title:
Point Taken: A gamified Intervention that Creates Enlightened Disagreements
Abstract:
Should we drop standardized testing for college or Ph.D. admissions? Allow athletes to join teams based on gender identity? When organizational and public policies bind behavior, human coexistence requires a way to determine that collective policy. Because individuals and like-minded groups have incomplete information, constrained strategies, and biased perspectives, thoughtful debate on those policies is critical. Unfortunately, those debates too often degrade into chaotic fights.
Point Taken provides a scalable solution by translating best practices in conflict resolution and critical thinking into a structured dialogue that can be learned and played in 30 minutes. In this interactive session, you'll play a short game to feel its effects.
Players replace persuasion with a common goal of discovering why they disagree. Dialogue then unfolds thoughtfully and calmly, through chains of short written reasons and responses. We've tested the game extensively in schools and organizations, and conducted a formal pilot study. All show powerful improvements in the tone and quality of debate, across longstanding and strongly-held disagreements. I’ll give background on best practices for enlightened disagreement, show how they translate to the game, ask you to play a game, and then ask for your advice on next steps.
Speaker Bio:
Steven Franconeri is leading scientist, teacher, and speaker on visual thinking, visual communication, and the psychology of data visualization. He is a Professor of Psychology in the Weinberg College of Arts & Sciences at Northwestern, Director of the Northwestern Cognitive Science Program, as well as a Kellogg Professor of Management and Organizations by Courtesy. He is the director of the Visual Thinking Laboratory, where a team of researchers explore how leveraging the visual system - the largest single system in your brain - can help people think, remember, and communicate more efficiently.
His undergraduate training was in computer science and cognitive science at Rutgers University, followed by a Ph.D. in Experimental Psychology from Harvard University, and postdoctoral research at the University of British Columbia. His work on both Cognitive Science and Data Visualization has been funded by the National Science Foundation, as well as the Department of Education, and the Department of Defense. He has received a prestigious National Science Foundation CAREER award, given to researchers who combine excellent research with outstanding teaching, and he has received a Psychonomic Society Early Career award for his research on visual thinking.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/97198523514
PW: NICO26
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, March 11, 2026 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)