Events
Past Event
WED@NICO SEMINAR: Brian Munsky, Colorado State University "Measuring and Predicting the Central Dogma of Molecular Biology - One Molecule at a Time"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speaker:
Brian Munsky, Assistant Professor. Chemical and Biological Engineering, Colorado State University
Title:
Measuring and Predicting the Central Dogma of Molecular Biology - One Molecule at a Time
Abstract:
Modern experimental advances have made it possible to measure DNA, RNA, and protein dynamics at the level of single molecules in single cells. These discrete data are often noisy, but they can be highly informative, especially when they are combined with advanced computational models. I will present a few recent advances in the integration of discrete stochastic models with different single-cell assays. First, I will introduce modern single-molecule experiments that are used to quantify mRNA and protein dynamics in fixed or live cells. Next, we will discuss the derivation of strict bounds on the likelihood that observed single-cell data could have come from hypothesized regulatory models, and we will show how these bounds can be used to reduce computational efforts with no sacrifice to accuracy or precision. Then we will explore new computational approaches to design optimal single-cell experiments to maximize the expected information contained within an experiment. We will illustrate the integration of these experimental and computational tools to build predictive models for mechanistic biochemical processes in yeast and human cells, including spatiotemporal cell-signaling, single-gene transcription activation, nascent mRNA elongation, mRNA transport, mRNA-translation activation, and sequence-dependent nascent protein elongation. Finally, we will discuss how discrete stochastic quantitative models can be used to extend the capabilities of super-resolution microscopy and make it possible to measure more molecular species within a single experiment.
Speaker Bio:
Brian Munsky earned B.S. and M.S. degrees in Aerospace Engineering from Penn State University in 2000 and 2002, and a Ph.D. in Mechanical Engineering from UC Santa Barbara in 2008. He then conducted research at the Los Alamos National Laboratory — as a Director’s Postdoctoral Fellow (2008-2010), as a Richard P. Feynman Distinguished Postdoctoral Fellow in Theory and Computing (2010-2013), and as a Staff Scientist (2013). Dr. Munsky joined the Department of Chemical and Biological Engineering and the School of Biomedical Engineering as an assistant professor in 2014. Brian is best known for his discovery of Finite State Projection algorithm, which has enabled inference of efficient and predictive models of single-cell gene regulation in bacteria, yeast and human cells. Brian was the recipient of the 2008 UCSB Department of Mechanical Engineering best Ph.D. Dissertation award, the 2010 Leon Heller Postdoctoral Publication Prize, and the 2012 LANL Postdoc Distinguished Performance Award for his work in this topic. Since joining CSU, Brian has received multiple research grants including the W M Keck Foundation grant (co-PI with Dr. Timothy Stasevich at CSU) and the NIH-NIGMS Maximizing Investigators’ Research Award (MIRA) for Early State Investigators. Dr. Munsky is also the contact organizer of the internationally recognized, NIH-funded q-bio summer school, where he runs single-cell stochastic gene regulation (q-bio.org).
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems and data science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between.
Live Stream:
Time
Wednesday, April 18, 2018 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Gary Slutkin, Cure Violence Global "The End of Violence - How do we do that?" (co-sponsored with CORNERS)
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speaker:
Gary Slutkin, Founder, Cure Violence Global
Title:
The End of Violence - How do we do that?
Abstract:
Dr. Slutkin will discuss the main findings in his new book The End of Violence - available from Hachette Book Group and other retailers on April 21, 2026.
After 20 years fighting epidemics of infectious diseases in the U.S., and abroad with the World Health Organization, Dr. Slutkin returned to Chicago and saw violence acting the same way as these other diseases. He then founded Cure Violence Global to show that violence not only behaves like other epidemics, but its spread can be interrupted and stopped using the same playbook. This approach is now being used widely and for many types of violence.
In this book, Dr. Slutkin reveals how we can now understand how violence spreads from person to person and from country to country, through invisible brain processes that can now be identified. He also found that both the contagion, and its interruption, can work for all forms of violence from child abuse to community violence, violence against women, suicide, and even war, genocide and tyranny. The book provides stories and data on success for several of these different forms of violence in Chicago, Baltimore, NYC, Honduras, Mexico, Colombia, Iraq, Syria and even to stop a potential nuclear war between the U.S. and North Korea.
With this new book, we now have not only a new diagnosis of violence – a disease - but a new method to stop it – with results in dozens of communities and countries, as well as a whole new understanding, language and even a whole new set or workers.
Speaker Bio:
Gary Slutkin is a physician and epidemiologist formerly of the World Health Organization, the Founder and CEO of Cure Violence, and an innovator in epidemic management, public health, behavior change, and data-based approaches to local and global problems.
He led or co-led efforts to reverse epidemics of tuberculosis and cholera in 40 refugee camps, led the efforts to start the national AIDS programs with the 13 countries in the epicenter of the epidemic in central and East Africa and, led World Health Organization’s efforts to reverse the AIDS epidemic in Uganda, the only country to successfully reverse its AIDS epidemic at the time. After 10 years abroad, Dr. Slutkin returned home to the U.S. and shifted his focus to violence, seeing it as an epidemic process. He is credited with having fully revealed the scientific and practical links for seeing and treating violence as a standard health epidemic. In the year 2000 he founded Cure Violence which has achieved 40% to 70% drops in violence in communities around the world using these methods. The approach has also been successfully adapted to curtail political violence, election violence, and gender-based violence in countries around the world.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/93101362874
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, networks, and artificial intelligence. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Co-Sponsor:
This speaker is co-sponsored with CORNERS.
Time
Wednesday, April 29, 2026 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
Data Science Nights - APRIL 2026 - Speaker: Joshua Stadlan, NICO and COMPASS
Northwestern Institute on Complex Systems (NICO)
5:00 PM
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M416, Technological Institute
Details
APRIL MEETING: Thursday, April 30, 2026 at 5:00pm (US Central)
LOCATION:
ESAM Conference Room, Tech M416
2145 Sheridan Road, Evanston, IL 60208
AGENDA:
PLEASE NOTE: this event is starting at 5pm this month.
5:00pm - Meet and greet with refreshments
5:30pm - Talk with Joshua Stadlan, Research Associate Professor, Northwestern Institute on Complex Systems (NICO); Core Faculty, Center for Computational & Social Sciences in Health (COMPASS)
TALK TITLE:
Why do we Socialize in Bursts? Using data and Particle Models to Study Human Interaction
ABSTRACT:
At large social events, conversations do not happen at a steady pace. Many are short and clustered together, while some last much longer or are separated by long gaps. This “burstiness” affects how people connect and how disease, news, or opinions spread through groups. In this talk, I use data and simple particle models to explore possible explanations for social burstiness. A common idea is that some people naturally attract more attention, which can generate burstiness. I show that simpler models can also generate burstiness, even without building in fixed differences between people. Join us in exploring how observational data and theory-driven modeling can together test explanations for patterns in our social lives.
DATA SCIENCE NIGHTS are monthly meetings featuring presentations and discussions about data-driven science and complex systems, organized by Northwestern University graduate students and scholars. Students and researchers of all levels are welcome! For more information: http://bit.ly/nico-dsn
FUTURE DATES:
Data Science Nights will be held on Thursday evenings in the winter and spring terms, with future dates May 28, 2026.
Time
Thursday, April 30, 2026 at 5:00 PM - 7:00 PM
Location
M416, Technological Institute Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Daniel Stouffer, Leibniz Institute "Conceptual and Theoretical Challenges in the Study of Multi-Species Coexistence"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speaker:
Daniel B. Stouffer, Research Group Leader, Department of Evolutionary and Integrative Ecology, the Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB), Berlin, Germany
Title:
Conceptual and Theoretical Challenges in the Study of Multi-Species Coexistence
Abstract:
The population dynamics of most ecological communities unfold on temporal scales that cannot be fully studied in the laboratory or field. The generation times of trees, for example, are so long and varied that we may need to wait decades to determine how a whole, interconnected forest community responds to a changing climate. Many researchers thus use models to generate predictions that go beyond the bounds of what is experimentally tractable. To do so, it has become common to follow the "model-paramerisation paradigm". For example, a researcher interested in forest dynamics would not conduct long-term experiments to directly probe whether one tree species is ever competitively excluded by any other(s). Instead, they would use data from shorter-term experiments to estimate the parameters of a presupposed model, and then study whether or not their empirically parameterised model predicts competitive exclusion or coexistence. As powerful as this perspective has proven to be, it routinely hinges on multiple key assumptions that limit its versatility. I will describe recent and ongoing work that challenges these assumptions, while also describing some unexpected hurdles encountered along the way.
Speaker Bio:
Daniel B. Stouffer is a Research Group Leader in the Department of Evolutionary and Integrative Ecology at the Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB), Berlin, Germany. His group adopts a variety of computational, statistical, and analytical approaches to overcome ecological communities' innate complexity while exploring fundamental biological questions. They work on a variety of topics and systems and are particularly interested in understanding the emergent ecological and evolutionary consequences that arise due to interactions between species.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/98364690035
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, networks, and artificial intelligence. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 6, 2026 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Hamsa Bastani, Wharton School, University of Pennsylvania "Challenges in Achieving Human-AI Collaboration"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
Speaker:
Hamsa Bastani, Associate Professor of Operations, Information, and Decisions, and Statistics and Data Science, Wharton School, University of Pennsylvania
Title:
Challenges in Achieving Human-AI Collaboration
Abstract:
TBA
Speaker Bio:
Hamsa Sridhar Bastani is an Associate Professor of Operations, Information, and Decisions (OID) and Statistics and Data Science at the Wharton School of the University of Pennsylvania, where she co-direct the Wharton Healthcare Analytics Lab. Her research sits at the intersection of machine learning, operations research, and economics. She studies how to design, deploy, and evaluate AI systems that empower human decision-makers and improve societal outcomes.
Professor Bastani aims to combine methodological depth with implementation in consequential environments. She has worked with national governments to deploy algorithms at the country scale for targeted border COVID-19 screening and essential medicine access, and has co-led one of the first large field studies of generative AI tutors in high school mathematics. She studies both the mathematical properties of algorithms and the way people respond to them.
Her research has been published in leading outlets including Nature, Management Science, Operations Research, and PNAS, and has garnered numerous recognitions, including the Wagner Prize for Excellence in Operations Research, the INFORMS Pierskalla Award for best healthcare paper, and the George Nicholson Prize. Previously, she graduated summa cum laude from Harvard in 2012 with an A.M. in physics and an A.B. in physics and mathematics, completed her PhD in Stanford's Electrical Engineering department under the supervision of Mohsen Bayati, and spent a year as a Herman Goldstine postdoctoral fellow at IBM Research.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/99847338986
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, networks, and artificial intelligence. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 13, 2026 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Lightning Talks with NU Scholars!
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details
NICO is looking for participants to share 12-15 minute lightning talks on their current research. To sign up, please fill out this short survey. These are open to Northwestern graduate students, postdoctoral fellows, and visiting scholars!
All talks will be given in person at Chambers Hall and this event will also be livestreamed via Zoom.
Speakers will be balanced based on their topics/disciplines in order to provide a broad representation of the research activities at NICO
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/98031689779
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, networks, and artificial intelligence. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 20, 2026 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)