Events
Past Event
WED@NICO SEMINAR: Shai Pilosof, University of Chicago "The dynamic and non-neutral population structure of the malaria parasite"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details

Title:
The dynamic and non-neutral population structure of the malaria parasite
Speaker:
Shai Pilosof - James S. McDonnell Foundation for Complex Systems Postdoctoral Scholar, University of Chicago
Talk Abstract:
Populations of the human malaria parasite, Plasmodium falciparum, comprise huge genetic diversity of relevance to recognition by the immune system. The population structure of the parasite in genetic, antigenic and temporal dimensions remains an important current question with foreseeable applications for malaria epidemiology. Theory predicts that competition for hosts, mediated by the selection that the immune system imposes on strains, can limit their genetic overlap and structure the parasite population. There is however little evidence for population structure in areas where transmission is endemic and the genetic diversity of the parasite is highly diverse, such as in sub-Saharan Africa. In this talk, I show how we used simulated and empirical networks of genetic similarity between strains to identify signatures of competition between strains, and the role it plays in shaping the genetic structure of the parasite’s population both statically and in time. Our approach is relevant to other dynamic biological systems with frequency-dependent interactions in a highly diverse trait space, and overlapping evolutionary and ecological time scales, such as microbial communities and several pathogen populations.
Speaker Bio:
Shai Pilosof is currently a James S. McDonnell Foundation for Complex Systems postdoctoral scholar at the University of Chicago, in the lab of Mercedes Pascual. He is mostly interested in the application of network theory to ecological systems, specifically in the field of disease ecology.
Live Stream:
Time
Wednesday, October 25, 2017 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Lightning Talks w/ Northwestern Scholars!
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level, Chambers Hall
Details

Speakers:
Yessica Herrera, Visiting Scholar, Northwestern Institute on Complex Systems
Talk Title: The Body Speaks: Visual Patterns of Psychological Stress
Aakriti Kumar, Post-Doctoral Fellow, Northwestern Institute on Complex Systems
Talk Title: Evaluating Elements of Empathic Communication with Experts, Crowds, and Large Language Models
Tingyu "Mark" Zhao, PhD Student, Industrial Engineering and Management Sciences
Talk Title: Noise Filtering in Complex Networks
Sign Up:
Sign up to present at a future Lightning Talk session. NICO Lightning Talks are open to graduate students, postdoctoral fellows, and visiting scholars.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/95387714084
Passcode: NICO25
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 14, 2025 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
WED@NICO SEMINAR: Rosemary Braun, Northwestern University "The Scale of Life"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
//
Lower Level, Chambers Hall
Details

Speaker:
Rosemary Braun, Associate Professor, Department of Molecular Biosciences, Northwestern University
Title:
The Scale of Life
Abstract:
Living systems exhibit surprising and beautiful self-organization at all scales. At the atomic level, proteins self-assemble into macromolecular complexes. The function of these machines is orchestrated within the cell by regulatory networks, whose activity is in turn dictated by, and coordinated with, the cells environment. This coordination takes place across large spans of space and time: the size and lifetime of organisms as large as the blue whale. Populations and ecosystems of many organisms in turn exhibit remarkable emergent dynamics. Today, advances in single-cell assays enable us to probe the molecular state of every cell in a sample in high-dimensional detail. But is this the correct scale at which to probe living systems? What can we learn from this data, and how can we abstract from the microscopic details to macroscopic phenotypes? In this talk, I will discuss some of our recent work bridging the cell and tissue/organism scales, and discuss some challenges and opportunities for the future.
Speaker Bio:
Rosemary Braun is an Associate Professor of Molecular Biosciences, Applied Mathematics [ESAM], and Physics at Northwestern University. A theoretical physicist by training, she earned her PhD in Physics from the University of Illinois, followed by a Masters in Biostatistics from Johns Hopkins University. She completed her postdoctoral training at the National Cancer Institute (NIH) before joining Northwestern as a faculty member. Today, she works at the intersection of statistics, mathematics, and biology to develop computational tools for analyzing high-dimensional data. In addition to her Northwestern affiliations, she is also Associate Director of the National Institute for Theory and Mathematics in Biology, as well as external faculty of the Santa Fe Institute.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
Remote option: https://northwestern.zoom.us/j/97015976754
Passcode: NICO25
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, May 21, 2025 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)