Events
Past Event
WED@NICO SEMINAR: Natalia Komarova, University of California, Irvine "Stochastic calculus of stem cells"
Northwestern Institute on Complex Systems (NICO)
12:00 PM
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Lower Level Chambers Hall
Details
![Natalia Komarova](
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Title:
Stochastic calculus of stem cells
Speaker:
Natalia Komarova - Professor, Department of Mathematics, University of California, Irvine
Talk Abstract:
Stem cells are an important component of tissue architecture. Identifying the exact regulatory circuits that can stably maintain tissue homeostasis (that is, approximately constant size) is critical for our basic understanding of multicellular organisms. It is equally critical for figuring out how tumors circumvent this regulation, thus providing targets for treatment. Despite great strides in the understanding of the molecular components of stem-cell regulation, the overall mechanisms orchestrating tissue homeostasis are still far from being understood. Typically, tissue contains the stem cells, transit amplifying cells, and terminally differentiated cells. Each of these cell types can potentially secrete regulatory factors and/or respond to factors secreted by other types. The feedback can be positive or negative in nature. This gives rise to a bewildering array of possible mechanisms that drive tissue regulation. In this talk I describe a novel stochastic method of studying stem cell lineage regulation, which is based on population dynamics and ecological approaches. The method allows to identify possible numbers, types, and directions of control loops that are compatible with stability, keep the variance low, and possess a certain degree of robustness. I will also discuss evolutionary optimization and cancer-delaying role of stem cells.
Live Stream:
To join the Meeting: bluejeans.com/8474912527
To join via Browser: bluejeans.com/8474912527/browser
Time
Wednesday, May 3, 2017 at 12:00 PM - 1:00 PM
Location
Lower Level Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)
Fall 2024 Classes Begin (No Northwestern Monday in Fall)
University Academic Calendar
All Day
Details
Fall 2024 Classes Begin (No Northwestern Monday in Fall)
Time
Tuesday, September 24, 2024
Contact
Calendar
University Academic Calendar
WED@NICO Seminar Series returns October 2024
Northwestern Institute on Complex Systems (NICO)
12:00 PM
//
Lower Level, Chambers Hall
Details
![NICO Logo](
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The Wednesdays@NICO speaker series with return on Wednesday, October 2, 2024. Speakers will be announced in September.
We welcome speaker suggestions from the NICO community. Please use this form to nominate a speaker.
Location:
In person: Chambers Hall, 600 Foster Street, Lower Level
About the Speaker Series:
Wednesdays@NICO is a vibrant weekly seminar series focusing broadly on the topics of complex systems, data science and network science. It brings together attendees ranging from graduate students to senior faculty who span all of the schools across Northwestern, from applied math to sociology to biology and every discipline in-between. Please visit: https://bit.ly/WedatNICO for information on future speakers.
Time
Wednesday, October 2, 2024 at 12:00 PM - 1:00 PM
Location
Lower Level, Chambers Hall Map
Contact
Calendar
Northwestern Institute on Complex Systems (NICO)