Speaker:

William Schnaper, MD - Professor of Pediatrics, Feinberg School of Medicine, Northwestern University.

Talk Abstract:

William Schnaper, Lauren Marsillio and Michael Kelleher

Recently, the Northwestern University Clinical and Translational Sciences (NUCATS) Institute received a TL1 training grant from the National Institutes of Health. We chose a novel task of training postdoctoral fellows (either clinical fellows in pediatrics or basic research fellows in engineering) to apply engineering solutions to problems in pediatric and adolescent health. Each fellow would have a mentor in both science and clinical pediatrics, and receive a salary stipend to protect their research time. We now have nine fellows who are addressing such problems as: How can natural language processing be used on the electronic health record help us optimize discharge planning? Can a servomechanism be developed for for delivering regional anesthesia to infants and young children? What is the best way to deliver antisense oligonucleotides to brain tumors? Can advanced data extraction methods be used to improve the recruitment of children for clinical trials? The long-term goal of this training program is to nucleate further collaboration among these disparate disciplines in order to develop a unique and nationally recognized program for innovative health research. The speakers will review potential projects that have been proposed, and describe a specific initiative in the pediatric intensive care unit at Lurie Children's that combines real-time analysis of high-resolution, physiologic data with data extracted from the electronic medical record and other medical devices in order to assess risk of morbidity and mortality in critically ill pediatric patients.

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